BSc, MSc, DPhil
Senior Medical Statistician
Marialena’s main area of work is systematic reviews and meta-analysis. She focuses on methodology systematic reviews of cancer prognosis, including reviews using individual participant data. She also regularly provides training on systematic reviews in both internal and external courses.
Marialena obtained a BSc in Mathematics from University College London (UCL), followed by an MSc in Medical Statistics from the University of Southampton and a DPhil from the University of Oxford.
She first worked at the National Health Service (NHS) and the University of Bristol. She joined the Centre for Statistics in Medicine (CSM) in 1999, where she worked on prognostic studies in lung cancer and developed an expertise in individual patient data meta-analysis and systematic reviews. She then joined the London School of Hygiene and Tropical Medicine (LSHTM) and the Royal College of Surgeons as a lecturer in Medical Statistics, from where she left in 2010 to join the UK Cochrane Centre as a Lecturer in Systematic Reviews.
Marialena rejoined the CSM in 2012 as a senior medical statistician in prognostic systematic reviews.
During her long-standing association with the Cochrane Collaboration (since 2005), Marialena spent two years working as a Cochrane Collaboration Training co-ordinator. She has contributed to the creation of 12 online training modules for systematic reviews, offered to Cochrane authors. She is also a statistical editor for the Cochrane Library, and works with a number of Cochrane groups as a statistician and methodologist.
Marialena works as a senior methodological and statistical advisor for the Systematic Review Initiative at the Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee.
She also had an advisory role on systematic reviews on infant feeding and development of atopic and autoimmune diseas, carried out Imperial College London on behalf of the UK Food Standards Agency.
Desborough M. et al, (2015), Cochrane Database Syst Rev
Siristatidis C. et al, (2013), Hum Reprod Update, 19, 105 - 123
Reoperation rates after breast conserving surgery for breast cancer among women in England: retrospective study of hospital episode statistics.
Jeevan R. et al, (2012), BMJ, 345
Trivella M. et al, (2007), Lancet Oncol, 8, 488 - 499
Effect of restrictive versus liberal red cell transfusion strategies on haemostasis: systematic review and meta-analysis
Desborough M. et al, (2017), Thrombosis and Haemostasis
Hamilton TW. et al, (2017), Cochrane Database Syst Rev, 2
Estcourt L. et al, (2017), Cochrane Database of Systematic Reviews
Estcourt LJ. et al, (2017), Cochrane Database Syst Rev, 1
Estcourt L. et al, (2017), Cochrane Database of Systematic Reviews, 2017