Aging, Alzheimer's disease, and dementia
BOOST: Better Outcomes for Older People with Spinal Trouble
BOOST is a programme of research to improve the management of lower back pain in older adults. It will explore and hopefully counter prejudices held by older people and clinicians. The programme includes qualitative research and a large cohort study of 4000 participants over 65 years from primary care with and without back pain. It also includes a randomised control trial to evaluate a physiotherapy programme for people with neurogenic claudication, a condition arising from ageing changes within the spine that is common in older people and can severely limit their ability to walk and stand.
ELAD: Evaluating the effects of the novel GLP-1 analogue liraglutide in patients with Alzheimer’s disease
ELAD tests whether a known treatment for diabetes, liraglutide, is able to improve memory in patients with Alzheimer's disease. This registered trial is run by the Neurology Imaging Unit of Imperial College London. It is currently recruiting participants.
Caring for Me and You: A toolkit for carers of people with dementia
The Fullbrook Centre at the Churchill hospital is running this randomised controlled trial, sponsored by the Oxford Health NHS Foundation Trust. It investigates whether online cognitive behavioural therapy (CBT), with or without telephone support, is effective in reducing stress and improving coping strategies in carers of people with dementia.
This trial is currently recruiting participants. If you care for someone with dementia and are interested in participating, please read more here.
Other clinical research
Interventions for Pain in Dementia
Around 80% of people with dementia in care homes experience regular pain, caused by conditions like arthritis or pressure sores from extended time in bed. Dr Anne Corbett of Kings College London is developing a pain management pathway for people with dementia living in care homes. She is funded by an NIHR Programme Development Grant.
The pathway will be optimised and tested in a clinical trial in a future research programme, followed by extensive work to implement it in care homes in the UK.