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Protocol

The DELTA2 protocol has now been published and is freely available:

Cook JA, Julious SA, Sones W, Rothwell JC, Ramsay CR, Hampson LV, Emsley R, Walters SJ, Hewitt C, Bland MJ, Fergusson DA, Berlin J, Altman D, Vale LD. Choosing the target difference ("effect size") for a randomised controlled trial - DELTA2 guidance protocol. Trials. 2017; 18: 271. https://doi.org/10.1186/s13063-017-1969-5