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Aim The aim of this study was to compare the cost-effectiveness of intramedullary nail fixation and 'locking' plate fixation in the treatment of extra-articular fractures of the distal tibia. Patients and Methods An economic evaluation was conducted from the perspective of the United Kingdom National Health Service (NHS) and personal social services (PSS), based on evidence from the Fixation of Distal Tibia Fractures (UK FixDT) multicentre parallel trial. Data from 321 patients were available for analysis. Costs were collected prospectively over the 12-month follow-up period using trial case report forms and participant-completed questionnaires. Cost-effectiveness was reported in terms of incremental cost per quality adjusted life year (QALY) gained, and net monetary benefit. Sensitivity analyses were conducted to test the robustness of cost-effectiveness estimates. Results Mean NHS and PSS costs were significantly lower for patients treated with an intramedullary nail than for those treated with a locking plate (-£970, 95% confidence interval (CI) -1685 to -256; p = 0.05). There was a small increase in QALYs gained in the nail fixation group (0.01, 95% CI -0.03 to 0.06; p = 0.52). The probability of cost-effectiveness for nail fixation exceeded 90% at cost-effectiveness thresholds as low as £15 000 per additional QALY. The cost-effectiveness results remained robust to several sensitivity analyses. Conclusion This trial-based economic evaluation suggests that nail fixation is a cost-effective alternative to locking plate fixation. Cite this article: Bone Joint J 2018;100-B:624-33.

Original publication

DOI

10.1302/0301-620X.100B5.BJJ-2017-1329.R2

Type

Journal article

Journal

Bone joint j

Publication Date

01/05/2018

Volume

100-B

Pages

624 - 633

Keywords

Cost utility, Cost-effectiveness, Distal tibia fractures, Economic evaluation, Intramedullary nail fixation, Locking plate fixation, Randomized controlled trial, Bone Plates, Cartilage, Articular, Cost-Benefit Analysis, Female, Fracture Fixation, Internal, Fracture Fixation, Intramedullary, Humans, Male, Middle Aged, Prospective Studies, Randomized Controlled Trials as Topic, Surveys and Questionnaires, Tibial Fractures