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We looked at our HIV + slow progressors cohort to determine if there were any human leukocyte antigen (HLA) correlates for protection. No statistically significant allelic differences were found between the HIV + and control cohorts using regression analysis, though trends were noted. Data for Elite Controllers showed an increased frequency of B*57. Likewise, no correlation was inferred with the clinical data of the HIV + cohort. We hypothesize that the protective effect of HLA alleles may have been lost over time.

Original publication

DOI

10.1097/QAD.0000000000000011

Type

Journal article

Journal

AIDS

Publication Date

13/11/2013

Volume

27

Pages

2822 - 2824

Keywords

China, Cohort Studies, Gene Frequency, HIV Infections, HIV Long-Term Survivors, Humans, Phosphoproteins